Modeling the effect of umbilical cord clamping | 寵物協尋網
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由MBYigit著作·2015·被引用45次—...RumelifeneriYolu,Sariyer,Istanbul,Turkey.Electronicaddress:[email protected]:25773588;DOI:10.1016/j.jbiomech.2015.02.040 ...
![Modeling the effect of umbilical cord clamping](https://i.imgur.com/voy7JL0.jpg)
Hemodynamics of the fetal to neonatal transition are orchestrated through complex physiological changes and results in cardiovascular adaptation to the adult biventricular circulation. Clinical practice during this critical period can influence vital organ physiology for normal newborns, premature babies and congenital heart defect patients. Particularly, the timing of the cord clamping procedure, immediate (ICC) vs. delayed cord clamping (DCC), is hypothesized to be an important factor for the transitory fetal hemodynamics. The clinical need for a quantitative understanding of this physiology motivated the development of a lumped parameter model (LPM) of the fetal cardio-respiratory system covering the late-gestation to neonatal period. The LPM was validated with in vivo clinical data and then used to predict the effects of cord clamping procedures on hemodynamics and vital gases. Clinical time-dependent resistance...
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