DIM | 寵物協尋網
![DIM](https://i.imgur.com/voy7JL0.jpg)
由SUKang著作·2021·被引用5次—Electronicaddress:[email protected]:33556544;DOI:10.1016/j.canlet.2021.01.005 ...
![DIM](https://i.imgur.com/voy7JL0.jpg)
Despite technological advances in cancer treatment, the survival rate of patients with head and neck cancer (HNC) has not improved significantly. Many studies have shown that endoplasmic reticulum (ER) stress-related signals are associated with mitochondrial damage and that these signals determine whether cells maintain homeostasis or activate cell death programs. The unfolded protein response (UPR) is regulated by ER membrane proteins such as double-stranded RNA-activated protein kinase R(PKR)-like ER kinase (PERK), which directly activate transcription of chaperones or genes that function in redox homeostasis, protein secretion, or cell death programs. In this study, we focused on the role of mitophagy and ER stress-mediated cell death induced by DIM-C-pPhtBu in HNC cancer. We found that DIM-C-pPhtBu, a compound that activates ER stress in many cancers, induced lysosomal dysfunction, excessive mitophagy, and cell ...
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約克夏-毛毛遺失 - SLIVER短毛 0002105D3E
於「大業路和健行路口」遺失的約克夏毛毛,以下提供飼主姓名、電話、Email,以及晶片號碼、寵物外觀及特徵等資訊,如果你有...